PGPEP1 Antibody

Code CSB-PA017874GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PGPEP1
Alternative Names
2810003H13Rik antibody; 5 oxoprolyl peptidase antibody; 5-oxoprolyl-peptidase antibody; FLJ20208 antibody; MGC10812 antibody; PAP I antibody; PAP-I antibody; PAPI antibody; Pcp antibody; PGI antibody; pGlu peptidase I antibody; PGP antibody; PGP I antibody; PGP-I antibody; Pgpep1 antibody; PGPI antibody; PGPI_HUMAN antibody; Pyroglutamyl aminopeptidase I antibody; Pyroglutamyl peptidase 1 antibody; pyroglutamyl peptidase I antibody; Pyroglutamyl-peptidase 1 antibody; Pyroglutamyl-peptidase I antibody; pyrrolidone carboxylate peptidase antibody; Pyrrolidone-carboxylate peptidase antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PGPEP1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
Gene References into Functions
  1. cytosolic peptidases(puromycin-sensitive aminopeptidase (PSA), aminopeptidase B (APB) and pyroglutamyl-peptidase I (PGI) ) may be involved in colorectal carcinogenesis PMID: 26078706
  2. The specific reduction of the levels of pyroglutamyl-aminopeptidase activity in serum of liver cirrhosis patients might be considered as a potential candidate to be included in a combination of markers for the diagnosis of this disease. PMID: 25687677
  3. cloning and sequencing of the human (AJ278828) pyroglutamyl-peptidase I PMID: 12651114
  4. VX-710 modulates Pgp, MRP-1, and BCRP(R482), and has potential as a clinical broad-spectrum multidrug resistance modulator in malignancies. PMID: 15014037
  5. The activities of pyroglutamyl peptidase I and prolyl endopeptidase in necrozoospermia were found to be higher in the corresponding soluble and particulate sperm fractions, respectively, with respect to those measured in normozoospermic semen PMID: 15380924

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Subcellular Location
Cytoplasm.
Protein Families
Peptidase C15 family
Database Links

HGNC: 13568

OMIM: 610694

KEGG: hsa:54858

STRING: 9606.ENSP00000269919

UniGene: Hs.131776

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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