PMM1 Antibody

Datasheet

Code	CSB-PA018237GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q92871

Target Names

PMM1

Alternative Names

Brain glucose-1,6-bisphosphatase antibody; Phosphomannomutase 1 antibody; PMM 1 antibody; pmm1 antibody; PMM1_HUMAN antibody; PMMH 22 antibody; PMMH-22 antibody; PMMH22 antibody; Sec53 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human PMM1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain.

Gene References into Functions

a triple mutant of phospomannomutase1 that retains mutase and phosphatase activity, but is unable to bind inosine monophosphate, was characterized. PMID: 29261720
Mutations in phosphomannomutase is associated with ophthalmic manifestations of congenital disorder of glycosylation type 1a PMID: 12789572
human alpha-phosphomannomutase 1 crystallographic structure reveals the structural basis of congenital disorder of glycosylation type 1a PMID: 16540464
analysis of mental development in a patient with phosphomannomutase deficiency who is compound heterozygous for T237R/C241S mutations [case report] PMID: 17186415
The genes GUS and PMM1 are recommended for normalization purposes in gene expression studies of liver tissue from patients with chronic hepatitis. PMID: 18591914
PMM1 is responsible for the degradation of Glc-1,6-P(2) in brain PMID: 18927083

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Subcellular Location

Cytoplasm.

Protein Families

Eukaryotic PMM family

Tissue Specificity

Strong expression in liver, heart, brain, and pancreas; lower expression in skeletal muscle.

Database Links

HGNC: 9114

OMIM: 601786

KEGG: hsa:5372

STRING: 9606.ENSP00000216259

UniGene: Hs.75835

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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