POP4 Antibody

Code CSB-PA018373ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA018373ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA018373ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) POP4 Polyclonal antibody
Uniprot No.
Target Names
POP4
Alternative Names
POP4 antibody; RPP29 antibody; Ribonuclease P protein subunit p29 antibody; hPOP4 antibody; EC 3.1.26.5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ribonuclease P protein subunit p29 protein (1-220AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Gene References into Functions
  1. Results demonstrate that Rpp29 promotes homology-directed repair of double-strand breaks. It is rapidly and transiently recruited to laser-microirradiated DNA sites. PMID: 28432356
  2. Collectively, the present results suggest that PhoRpp21 binds the loop between P11 and P12 helices through overall positively charged clusters on the surface of the complex and serves as a scaffold for PhoRpp29 to optimize structural conformation of its N-terminal helix (alpha2) in PhoRpp21, as well as C-terminal residues in PhoRpp29, for RNase P activity. PMID: 27810361
  3. Rpp29 represses H3.3 nucleosome deposition, a finding with implications for epigenetic regulation. PMID: 26842893
Subcellular Location
Nucleus, nucleolus.
Protein Families
Eukaryotic/archaeal RNase P protein component 1 family
Database Links

HGNC: 30081

OMIM: 606114

KEGG: hsa:10775

STRING: 9606.ENSP00000465213

UniGene: Hs.412870

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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