PRSS56 Antibody

Code CSB-PA317372LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Rat liver tissue, Rat spleen tissue
    All lanes: PRSS56 antibody at 3μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 65 kDa
    Observed band size: 65 kDa

  • Immunohistochemistry of paraffin-embedded human eye tissue using CSB-PA317372LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PRSS56 Polyclonal antibody
Uniprot No.
Target Names
PRSS56
Alternative Names
PRSS56 antibody; Serine protease 56 antibody; EC 3.4.21.- antibody
Raised in
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant Human Serine protease 56 protein (36-116AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PRSS56 Antibody (Product code: CSB-PA317372LA01HU) is Non-conjugated. For PRSS56 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA317372LB01HU PRSS56 Antibody, HRP conjugated ELISA
FITC CSB-PA317372LC01HU PRSS56 Antibody, FITC conjugated
Biotin CSB-PA317372LD01HU PRSS56 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Serine protease required during eye development.
Gene References into Functions
  1. variations in PRSS56 were evaluated in patients with either primary angle-closure glaucoma (PACG) or high hyperopia. PMID: 24227917
  2. Idenification of a founder mutation in the PRSS56 gene in Tunisian families with posterior microphthalmia and nanophthalmia. PMID: 23820083
  3. Corneal diameter decreases with decreasing axial length, suggesting posterior microphthalmos and nanophthalmos represent a spectrum of high hyperopia rather than distinct phenotypes. In the Saudi population PRSS56 mutations are the major cause. PMID: 23127749
  4. PRSS56 is a good candidate for the causal gene for nanophthalmos in a Mexican-Canadian family cohort. PMID: 21850159
  5. Together, these data suggest that alterations of this serine protease may contribute to a spectrum of human ocular conditions including reduced ocular size and ACG. PMID: 21532570
  6. Three different mutations in PRSS56, were detected in microphthalmos patients of the Faroese families. PMID: 21397065

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Involvement in disease
Microphthalmia, isolated, 6 (MCOP6)
Protein Families
Peptidase S1 family
Tissue Specificity
Expressed neural retina, cornea, sclera and optic nerve.
Database Links

HGNC: 39433

OMIM: 613517

KEGG: hsa:646960

UniGene: Hs.570310

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