PRSS56 Antibody

Code CSB-PA317372LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Rat liver tissue, Rat spleen tissue
    All lanes: PRSS56 antibody at 3μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 65 kDa
    Observed band size: 65 kDa

  • Immunohistochemistry of paraffin-embedded human eye tissue using CSB-PA317372LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PRSS56 Polyclonal antibody
Uniprot No.
Target Names
PRSS56
Alternative Names
PRSS56 antibody; Serine protease 56 antibody; EC 3.4.21.- antibody
Raised in
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant Human Serine protease 56 protein (36-116AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PRSS56 Antibody (Product code: CSB-PA317372LA01HU) is Non-conjugated. For PRSS56 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA317372LB01HU PRSS56 Antibody, HRP conjugated ELISA
FITC CSB-PA317372LC01HU PRSS56 Antibody, FITC conjugated
Biotin CSB-PA317372LD01HU PRSS56 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Serine protease required during eye development.
Gene References into Functions
  1. variations in PRSS56 were evaluated in patients with either primary angle-closure glaucoma (PACG) or high hyperopia. PMID: 24227917
  2. Idenification of a founder mutation in the PRSS56 gene in Tunisian families with posterior microphthalmia and nanophthalmia. PMID: 23820083
  3. Corneal diameter decreases with decreasing axial length, suggesting posterior microphthalmos and nanophthalmos represent a spectrum of high hyperopia rather than distinct phenotypes. In the Saudi population PRSS56 mutations are the major cause. PMID: 23127749
  4. PRSS56 is a good candidate for the causal gene for nanophthalmos in a Mexican-Canadian family cohort. PMID: 21850159
  5. Together, these data suggest that alterations of this serine protease may contribute to a spectrum of human ocular conditions including reduced ocular size and ACG. PMID: 21532570
  6. Three different mutations in PRSS56, were detected in microphthalmos patients of the Faroese families. PMID: 21397065

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Involvement in disease
Microphthalmia, isolated, 6 (MCOP6)
Protein Families
Peptidase S1 family
Tissue Specificity
Expressed neural retina, cornea, sclera and optic nerve.
Database Links

HGNC: 39433

OMIM: 613517

KEGG: hsa:646960

UniGene: Hs.570310

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