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PRTFDC1 Antibody

Datasheet
Code CSB-PA018827GA01HU
Size $600
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Product Details

Uniprot No.
Q9NRG1
Target Names
PRTFDC1
Alternative Names
FLJ11888 antibody; HHGP antibody; OTTHUMP00000019332 antibody; Phosphoribosyl transferase domain containing 1 antibody; phosphoribosyltransferase domain containing protein 1 antibody; Phosphoribosyltransferase domain-containing protein 1 antibody; PRDC1_HUMAN antibody; prtfdc1 antibody; Uncharacterized protein PRTFDC1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human PRTFDC1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

PRTFDC1 Antibodies

PRTFDC1 Proteins

Customer Reviews and Q&A

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Target Background

Function
Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage.
Gene References into Functions
  1. We found evidence for PRTFDC1 as a potential novel PTSD gene, a finding that awaits further replication. PMID: 25456346
  2. These results demonstrate that PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse. PMID: 21818316
  3. The PRTFDC1 structure has been determined at 1.7 A resolution with bound GMP. The overall structure and GMP binding mode are very similar to that observed for HPRT. PMID: 21054786
  4. epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PMID: 17599052
Protein Families
Purine/pyrimidine phosphoribosyltransferase family
Database Links

HGNC: 23333

OMIM: 610751

KEGG: hsa:56952

STRING: 9606.ENSP00000318602

UniGene: Hs.405619

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