RAB26 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA892347LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RAB26 Polyclonal antibody

Uniprot No.

Q9ULW5

Target Names

RAB26

Alternative Names

CATX-8 antibody; RAB11c antibody; Rab26 antibody; RAB26 member RAS oncogene family antibody; RAB26_HUMAN antibody; Ras related oncogene protein antibody; Ras related protein Rab 26 antibody; Ras-associated protein Rab26 antibody; Ras-related protein Rab-26 antibody; V46133 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Ras-related protein Rab-26 protein (1-58AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland.

Gene References into Functions

Rab26 selectively directs synaptic and secretory vesicles into preautophagosomal structures. PMID: 25643395
Increased RAB26 expression causes lysosomes to coalesce in a central, perinuclear region within the cell. PMID: 24413166
The small GTPase Rab26 regulates the Golgi to cell surface traffic of alpha(2)-adrenergic receptors, likely through a physical interaction. PMID: 23105096
MIST1 binds to highly conserved CATATG E-boxes to directly activate transcription of 6 genes, including those encoding the small GTPases RAB26 and RAB3D. PMID: 20038531

Subcellular Location

Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle membrane; Lipid-anchor; Cytoplasmic side.

Protein Families

Small GTPase superfamily, Rab family

Tissue Specificity

Predominantly expressed in brain.

Database Links

HGNC: 14259

OMIM: 605455

KEGG: hsa:25837

STRING: 9606.ENSP00000210187

UniGene: Hs.3797

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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