RAB34 Antibody

1. The present study demonstrated that RAB34 plays an important role in the initiation and progression of hepatocellular carcinoma (HCC). Our results suggest a new therapeutic target for the clinical treatment of HCC. PMID: 29048615
2. Rab34 activity is modulated by SopD2 and is required for maturation of the Salmonella containing vacuole. PMID: 28185347
3. NARR is ubiquitously expressed and resides in nucleoli where it colocalizes with ribosomal DNA gene clusters. PMID: 21586586
4. MMP19 were positively correlated with RAB34. PMID: 25501506
5. Although Rab34 regulates both lysosomal positioning and lysosome to phagosome fusion, the latter effect is not due to the regulation of the cytoplasmic accessibility of lysosomes to phagosomes by Rab34. PMID: 23871933
6. Rab36 may regulate the spatial distribution of late endosomes and lysosomes through a similar mechanism to Rab34. PMID: 19961360
7. Data suggest that diacylglycerol-activated hmunc13 serves as an effector of Rab34, mediating lysosome-Golgi trafficking. PMID: 16138900
8. define Rab34 as a novel member of the secretory pathway acting at the Golgi PMID: 17881736
9. B coxsackievirus entry depends on occludin and require the activity of Rab34, Ras, and Rab5, GTPases known to regulate macropinocytosis. PMID: 18005733
10. mechanistic basis for high glucose-induced protein secretion is through interaction of munc13 and rab34, indicating a potentially critical role for this newly described pathway in the pathogenesis of DN. PMID: 19641095

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HGNC: 16519

OMIM: 610917

KEGG: hsa:83871

STRING: 9606.ENSP00000410403

UniGene: Hs.301853