RADIL Antibody

Code CSB-PA019275GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
RADIL
Alternative Names
RADIL antibody; KIAA1849 antibody; Ras-associating and dilute domain-containing protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human RADIL
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Downstream effector of Rap required for cell adhesion and migration of neural crest precursors during development.
Gene References into Functions
  1. Studies indicate that Radil regulates neutrophil adhesion and motility by linking Rap1 to beta2-integrin activation. +++ ERROR +++ studies establish that Radil regulates neutrophil adhesion and motility by linking Rap1 to beta2-integrin activation. PMID: 23097489
  2. It was shown that KIF14 associates with the PDZ domain of Radil and negatively regulates Rap1-mediated inside-out integrin activation by tethering Radil on microtubules. Radil is also important for breast cancer cell proliferation and metastasis. PMID: 23209302
  3. Gbetagamma subunits enter in a protein complex with activated Rap1a and its effector Radil; this complex is required downstream of receptor stimulation for the activation of integrins and the positive modulation of cell-matrix adhesiveness. PMID: 20048162
Protein Families
RADIL family
Database Links

HGNC: 22226

OMIM: 611491

KEGG: hsa:55698

STRING: 9606.ENSP00000382492

UniGene: Hs.667336

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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