RBAK Antibody

Code CSB-PA003952
Size US$100
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  • Western Blot analysis of HepG2 cells using RBAK Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
RBAK
Alternative Names
hRBaK antibody; Hypothetical protein RBAK antibody; RB associated KRAB zinc finger antibody; RB-associated KRAB repressor antibody; RB-associated KRAB zinc finger protein antibody; RBAK antibody; RBAK_HUMAN antibody; Zinc finger protein 769 antibody; ZNF 769 antibody; ZNF769 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of Human RBAK.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May repress E2F-dependent transcription. May promote AR-dependent transcription.
Gene References into Functions
  1. Studies indicate that data on the regulatory functions of the KRAB-ZFP in embryonic development and tumorgenesis will benefit the understanding of biological roles of KRAB-ZFP in different physiological and pathological states. PMID: 20466629
  2. RBaK interacts with the androgen receptor and increases its transcriptional activity. PMID: 14664718
  3. study found no evidence of mutations in the coding sequence and splice sites of RBaK in association with familial hyperaldosteronism type II PMID: 17121540
  4. The role of RBaK, PMS2, and GNA12 in the inheritance of familial hyperaldosteronism type II were studied. PMID: 18307725
Subcellular Location
Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Tissue Specificity
Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.
Database Links

HGNC: 17680

OMIM: 608191

KEGG: hsa:57786

STRING: 9606.ENSP00000275423

UniGene: Hs.396178

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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