RMND1 Antibody

Code CSB-PA882123LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: MCF-7 whole cell lysate, HEK293 whole cell lysate, Mouse skeletal muscle tissue
    All lanes: RMND1 antibody at 3µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 52, 28, 24 kDa
    Observed band size: 52 kDa

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA882123LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA882123LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA882123LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RMND1 Polyclonal antibody
Uniprot No.
Target Names
RMND1
Alternative Names
bA351K16 antibody; bA351K16.3 antibody; C6orf96 antibody; chromosome 6 open reading frame 96 antibody; FLJ20627 antibody; MGC117362 antibody; MGC149570 antibody; MGC882602 antibody; required for meiotic nuclear division 1 homolog (S. cerevisiae) antibody; Required for meiotic nuclear division protein 1 homolog antibody; Rmnd1 antibody; RMND1_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Required for meiotic nuclear division protein 1 homolog protein (35-160AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The RMND1 Antibody (Product code: CSB-PA882123LA01HU) is Non-conjugated. For RMND1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA882123LB01HU RMND1 Antibody, HRP conjugated ELISA
FITC CSB-PA882123LC01HU RMND1 Antibody, FITC conjugated
Biotin CSB-PA882123LD01HU RMND1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome.
Gene References into Functions
  1. Hearing impairment and renal failure are associated with RMND1 mutations. PMID: 26395190
  2. Expression of ESR1, RMND1 and CCDC170 associated with variants in separate enhancer elements predisposing breast cancer. [meta-analysis] PMID: 26928228
  3. Results demonstrate that the RMND1 complex is necessary for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome. PMID: 23022098
  4. The RMND1 mutation caused haploinsufficiency that was rescued by overexpression of the wild-type transcript in mutant fibroblasts; this overexpression increased the levels and activities of mitochondrial respiratory-chain proteins. PMID: 23022099
Involvement in disease
Combined oxidative phosphorylation deficiency 11 (COXPD11)
Subcellular Location
Mitochondrion.
Protein Families
RMD1/sif2 family
Database Links

HGNC: 21176

OMIM: 614917

KEGG: hsa:55005

STRING: 9606.ENSP00000356272

UniGene: Hs.486835

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