RNF14 Antibody

Datasheet

Code	CSB-PA080036
Size	US$119
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9UBS8

Target Names

RNF14

Alternative Names

Androgen receptor associated protein 54 antibody; Androgen receptor-associated protein 54 antibody; ARA 54 antibody; ARA54 antibody; E3 ubiquitin protein ligase RNF14 antibody; E3 ubiquitin-protein ligase RNF14 antibody; FLJ26004 antibody; HFB 30 antibody; HFB30 antibody; HRIHFB2038 antibody; RING finger protein 14 antibody; RNF 14 antibody; Rnf14 antibody; RNF14_HUMAN antibody; TRIAD 2 antibody; TRIAD2 antibody; Triad2 protein antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the C-terminal region of Human ARA54.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:40000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.

Gene References into Functions

Ring Finger Protein 14 (RNF14) is a binding partner for all TCF/LEF transcription factors. PMID: 23449499
dominant-negative AR coregulator can suppress AR transactivation and cell proliferation in prostate cancer cells PMID: 11673464
ARA54 role in prostate carcinoma progression may in may involve function as androgen receptor coactivator and focal adhesion protein PMID: 12772188
ARA54, might have dual in vivo roles functioning as both a direct coactivator and as an indirect mediator in AR function. PMID: 17082327
Dual functional roles for ARA54 as an AR coregulator directly and as a mediator for the suppressive effect of hnRNP A1 indirectly. PMID: 17110431
mRNA expression of ARA54 correlates with that of cyclin D1 in human colon carcinoma cells, indicating that ARA54 is not only involved in the regulation of cyclin D1 expression in cultured cell lines but also in clinical cancer specimens. PMID: 17510080
Differential localization of ARA54 may play an important role in testicular development and spermatogenesis in humans. PMID: 17919607

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Subcellular Location

Cytoplasm. Nucleus.

Protein Families

RBR family, RNF14 subfamily

Tissue Specificity

Widely expressed.

Database Links

HGNC: 10058

OMIM: 605675

KEGG: hsa:9604

STRING: 9606.ENSP00000324956

UniGene: Hs.483616

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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