RPL7 Antibody

1. HIV-1 Gag NC domain interacts with the ribosomal protein RPL7 endowed with nucleic acid chaperone activity, favoring the notion that RPL7 could be a Gag helper chaperoning factor possibly contributing to the start of Gag assembly PMID: 27515235
2. In case of L7, importin beta2 or importin beta3 are preferentially used by clusters with a high import efficiency. PMID: 23266416
3. RPL7 gene expression is decreased in follicular variant of papillary thyroid carcinoma. PMID: 21509594
4. importin beta3 is essential for the nuclear import of RPL7. The import is mediated via the multifaceted basic amino acid clusters present in the NH(2)-region of RPL7, and is RanGTP-dependent PMID: 20828572
5. Combining with the phylogenic findings from homologous sequence alignment, the NH2-region of L7, besides being as a eukaryotic expansion segment, can be excluded from building a functional eukaryotic ribosome. PMID: 16797011
6. L7-endoplasmic reticulum-binding nature could be one of multiple factors that allow a nascent peptide-less ribosome to remain at the endoplasmic reticulum. PMID: 17258209

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HGNC: 10363

OMIM: 604166

KEGG: hsa:6129

STRING: 9606.ENSP00000339795

UniGene: Hs.421257