SCAF1 Antibody

Code CSB-PA004050
Size US$100
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  • Western Blot analysis of Jurkat cells using SCAF1 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
SCAF1
Alternative Names
SCAF1 antibody; SFRS19 antibody; SRA1 antibody; Splicing factor antibody; arginine/serine-rich 19 antibody; SR-related C-terminal domain-associated factor 1 antibody; SR-related and CTD-associated factor 1 antibody; SR-related-CTD-associated factor antibody; SCAF antibody; Serine arginine-rich pre-mRNA splicing factor SR-A1 antibody; SR-A1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of Human SCAF1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May function in pre-mRNA splicing.
Gene References into Functions
  1. This is the first study that examines the expression of the novel gene SR-A1 in colon cancer progression. PMID: 15493872
  2. Study describes the discovery and cloning of fifteen novel splice variants of SCAF1 gene in cancer cells comprising a total of nine novel alternative splicing events between the annotated exons of the gene, producing seven novel SCAF1 transcripts with open-reading frames, and eight novel SCAF1 transcripts with premature termination codons that are likely long non-coding RNAs. Additionally, a novel 3' UTR was discovered. PMID: 29787824
  3. This study unveils the presence of SR-A1, CD36, and LOX-1 in aortic valves and suggests potential mechanisms by which they may contribute to the pathological angiogenesis, inflammation, calcification, and lipid accumulation in AVS. PMID: 24929820
  4. Our results suggest that SRA1 is associated with cancer progression and may possibly be characterized as a new marker of unfavorable prognosis for ovarian cancer. PMID: 16631123
Subcellular Location
Nucleus.
Protein Families
Splicing factor SR family
Tissue Specificity
Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa.
Database Links

HGNC: 30403

OMIM: 617264

KEGG: hsa:58506

STRING: 9606.ENSP00000353769

UniGene: Hs.103521

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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