SGK2 Antibody

1. Loss of the paternally derived allele of the imprinted SGK2 gene is associated with Shwachman-Diamond syndrome. PMID: 27553422
2. These findings suggest that SGK2 promotes hepatocellular carcinoma progression and mediates glycogen synthase kinase 3 beta/beta-catenin signaling in hepatocellular carcinoma cells. PMID: 28639896
3. SGK2 stimulated hOAT4 transport activity by abrogating the inhibitory effect of Nedd4-2 on the transporter. PMID: 26740304
4. Activation of hepatocyte pregnane X receptor is mediated through serum- and glucocorticoid-regulated kinase (SGK)2. PMID: 24204015
5. Glucocorticoid inducible kinase isoforms SGK1-3 are novel potent stimulators of Slc6a19 and may thus participate in the regulation of neutral amino acid transport in vivo. PMID: 20511718
6. Powerful stimulating effect of all three isoforms of SGK on K(+) channels. Those effects may participate in regulation of epithelial transport, cell proliferation, and neuromuscular excitability. PMID: 12397388
7. All three members of the SGK family of kinases SGK1-3 and protein kinase B stimulate the slowly activating K(+) channel KCNE1/KCNQ1. The kinases may thus participate in the regulation of KCNE1-dependent transport and excitability. PMID: 12634932
8. Co-expression of SGK1, but not of SGK2 or SGK3, increased Kv 4.3/KChIP2b channel currents. PMID: 15578212

Show More

Hide All

HGNC: 13900

OMIM: 607589

KEGG: hsa:10110

STRING: 9606.ENSP00000340608

UniGene: Hs.300863