SGSM3 Antibody

Code CSB-PA021203GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SGSM3
Alternative Names
Bdif 1 antibody; Cip85 antibody; Cx43 interacting protein of 85 kDa antibody; MAP antibody; Merlin associated protein antibody; merlin binding protein antibody; Merlin-associated protein antibody; R75178 antibody; rab GTPase activating protein like protein antibody; Rab-GTPase-activating protein-like protein antibody; RABGAP5 antibody; rabGAPLP antibody; RUN and SH3 containing 3 antibody; RUN and TBC1 domain containing 3 antibody; RUN and TBC1 domain containing protein 3 antibody; RUN and TBC1 domain-containing protein 3 antibody; RUN and TBC1 domains-containing protein 3 antibody; RUSC3 antibody; RUTBC3 antibody; SGSM3 antibody; SGSM3_HUMAN antibody; Small G protein signaling modulator 3 antibody; Small G protein signaling modulator 3 protein antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SGSM3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a cooperative role in NF2-mediated growth suppression of cells.
Gene References into Functions
  1. SGSM3 gene polymorphism is associated with the risk of breast cancer in Chinese population. PMID: 27432265
  2. The CIP85 was observed to interact with clathrin, which suggested a role for CIP85 in the clathrin-mediated internalization of Cx43. PMID: 23586710
  3. rs56228771 may contribute to hepatocarcinogenesis, possibly by affecting SGSM3 expression through a miRNA-mediated regulation. PMID: 23918301
  4. MAP decreased the AP-1-dependent promoter activity additively with merlin in NIH3T3 cells.Results suggest that MAP may play a cooperative role in the merlin-mediated growth suppression of cells. PMID: 15541357
  5. Identification of novel protein SGSM3 which modulates small G protein (RAP and RAB)-mediated signaling pathway. PMID: 17509819

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Subcellular Location
Cytoplasm.
Protein Families
Small G protein signaling modulator family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 25228

OMIM: 610440

KEGG: hsa:27352

STRING: 9606.ENSP00000248929

UniGene: Hs.474914

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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