SLC25A2 Antibody

Code CSB-PA021487GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SLC25A2
Alternative Names
SLC25A2; ORNT2; Mitochondrial ornithine transporter 2; Solute carrier family 25 member 2
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SLC25A2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.
Gene References into Functions
  1. characterized mutations of the proposed substrate binding site in ORC1 and ORC2; demonstrated that the residue at position 179 in the 2 soforms is largely responsible for the difference in their substrate specificity;concluded that Arg-179 is a key residue in the opening of the carrier to the matrix side PMID: 22262851
  2. expression, reconstitution, functional characterization, and tissue distribution of two human isoforms ORC1 and ORC2 PMID: 12807890
  3. Here we identify a new intronless gene, ORNT2, located on chromosome 5. PMID: 12948741
Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein Families
Mitochondrial carrier (TC 2.A.29) family
Tissue Specificity
Expressed in liver, kidney, pancreas and cultured fibroblasts.
Database Links

HGNC: 22921

OMIM: 608157

KEGG: hsa:83884

STRING: 9606.ENSP00000239451

UniGene: Hs.97647

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