SLC38A1 Antibody

1. High SNAT1 expression is associated with increased cell migration in breast neoplasms. PMID: 27048259
2. this study indicates that inhibition of miRNA-593-3p by insulin promotes glucose metabolism through the regulation of Slc38a1 and CLIP3 expression, and provides a new insight into the role and mechanism of insulin-induced glycolysis. PMID: 27613819
3. Results found that SLC38A1 was up-regulated in colorectal cancer cells (CRC) and significantly associated with tumor invasion and advanced disease stage. Its overexpression enhanced growth and migration of HCT116 cells providing evidence that activation of SLC38A1 may play a critical role in CRC development and progression. PMID: 28224429
4. The SLC38A1 protein was very low or undetectable in healthy gastric mucosa but strong staining of SLC38A1 protein was found in the cytoplasm in more than half of gastric cancer samples. SLC38A1 knockdown decreased tumor cell proliferation and migration. PMID: 24712400
5. The cross-talk between Akt signaling and SNAT1 might play a critical role in the development and progression of breast cancer PMID: 23848995
6. Increased expression of ATA1 is frequent in human hilar cholangiocarcinoma and significantly correlated with the progression of cholangiocarcinoma, suggesting the importance of ATA1 in cancer development and progression. PMID: 20605601
7. The results of this study provided that RAB2A and SLC38A1, were associated with the density of calbindin-positive neurons and the number of perineuronal oligodendrocytes in psychiatric disorders. PMID: 20308991
8. results suggest that slc38a1 may play a role in the mechanisms underlying the determination of cellular viability in astrocytes through modulation of intracellular ROS generation PMID: 21219957
9. SNAT1 is a key contributor to system A activity at term. PMID: 20599747
10. Theses data demonstrate the physiological importance of ATA1 in hepatocarcinogenesis. PMID: 17549407
11. Report SNAT1 activity in fetal T lymphocytes in intrauterine growth restriction and with tumor necrosis factor-alpha treatment. PMID: 18703994
12. A possible association between low expression of SNAT1 and suicidal behavior is suggested. PMID: 19442705

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HGNC: 13447

OMIM: 608490

KEGG: hsa:81539

STRING: 9606.ENSP00000381634

UniGene: Hs.533770