SOX13 Antibody

Code CSB-PA022421GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SOX13
Alternative Names
ICA 12 antibody; ICA12 antibody; Islet cell antibody 12 antibody; Islet cell antigen 12 antibody; MGC117216 antibody; SOX 13 antibody; SOX 13 protein antibody; sox13 antibody; SOX13 protein antibody; SOX13_HUMAN antibody; SRY (Sex determining region Y)-box 13 antibody; SRY box 13 antibody; SRY box containing gene 13 antibody; SRY related HMG box gene 13 antibody; SRY sex determining region Y box 13 antibody; Transcription factor SOX 13 antibody; Transcription factor Sox-13 antibody; Type 1 diabetes autoantigen antibody; Type 1 diabetes autoantigen ICA 12 antibody; Type 1 diabetes autoantigen ICA12 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SOX13
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'. Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube. Binds to the gene promoter of MBP and acts as a transcriptional repressor. Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells. Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells. Promotes brown adipocyte differentiation. Inhibitor of WNT signaling.
Gene References into Functions
  1. the interaction between Hhex and SOX13 may contribute to control Wnt/TCF1 signaling in the early embryo. PMID: 20028982
Subcellular Location
Nucleus. Cytoplasm.
Tissue Specificity
Expressed in exocrine cells and islets of Langerhans in the pancreas (at protein level). Expressed in the pancreas, placenta, kidney, brain, heart, lung, and liver. Expressed in adipose tissue, cervix, colon, esophagus, ovary, prostate, small intestine, s
Database Links

HGNC: 11192

OMIM: 604748

KEGG: hsa:9580

STRING: 9606.ENSP00000356172

UniGene: Hs.201671

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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