SP2 Antibody

1. This study presented that a Novel Mutation (Gly212Val) in the PS2 Gene Associated with Early-Onset Familial Alzheimer's Disease. PMID: 27128372
2. SP2 recognized binding motifs in the human RORgammaT promoter, which was critical for maintaining expression. SP2 was necessary for maximum IL-17 expression in in vitro-differentiated Th17 cells. SP 2 plays a role in Th17-dependent physiologic and pathologic immune responses. PMID: 27256574
3. O-GlcNAc modification of Sp3 and Sp4, but not Sp2 transcription factors negatively regulates their transcriptional activities. PMID: 26431879
4. Sp2 is up-regulated in gastric cancer tissues PMID: 24623314
5. Data show that three Sp1 motifs located between -148 and -42bp upstream of the first exon were important in basic as well as in DA-induced NSMase2 promoter activity. PMID: 19698806
6. an SP2/KLF6 repression complex by SHP is required for farnesoid X receptor-induced endothelial cell migration PMID: 17071613
7. Despite the absence of Sp2 in the 5'-upstream sequence of the human promoter, silencing of Sp2 by RNA interference clearly demonstrated that Sp2 is required for IFN-gamma-induced regulation of socs1 mRNA both in human and mouse. PMID: 19482358

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HGNC: 11207

OMIM: 601801

KEGG: hsa:6668

STRING: 9606.ENSP00000365931

UniGene: Hs.514276