SULT4A1 Antibody

Datasheet

Code	CSB-PA022944GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9BR01

Target Names

SULT4A1

Alternative Names

BR STL 1 antibody; Brain sulfotransferase like protein antibody; Brain sulfotransferase-like protein antibody; Brain sulphotransferase like antibody; BRSTL1 antibody; DJ388M5.3 antibody; hBR STL 1 antibody; hBR STL antibody; hBR-STL antibody; hBR-STL-1 antibody; MGC40032 antibody; Nervous system cytosolic sulfotransferase antibody; Nervous system sulfotransferase antibody; NST antibody; OTTHUMP00000028875 antibody; ST4A1 antibody; ST4A1_HUMAN antibody; Sulfotransferase 4A1 antibody; Sulfotransferase family 4A member 1 antibody; Sulfotransferase related protein antibody; SULT4A1 antibody; SULTX3 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human SULT4A1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS.

Gene References into Functions

These results show that SULT4A1 is widely expressed in human tissues, but mostly as a splice variant that produces a rapidly degraded protein. Dimerization protects the protein from degradation. PMID: 24988429
Across three psychiatric disorders (n=2815 patients), we observed no consistent association between SULT4A1-1 status and atypical antipsychotic effect PMID: 25340730
This study provides a second replication of superior olanzapine response in SULT4A1-1-positive subjects compared with SULT4A1-1-negative subjects. PMID: 24956247
determination of SULT4A1-1 haplotype status might be useful for identifying patients who show an enhanced response to long-term olanzapine treatment. PMID: 21521020
the first immunohistochemical localization of SULT4A1 in human brain PMID: 14623933
Candidate gene for schizophrenia susceptibility. PMID: 16152568
These results provide the first evidence of how genetic variation in Sult4A1 may be related to clinical symptoms and cognitive function in schizophrenia PMID: 18823757
The lack of polymorphisms in the coding region of the SULT4A1 gene is highly unusual and, along with its high conservation between species, suggests that SULT4A1 may have an important function in vivo. PMID: 19125109
Cytosolic SULT4A1 interacts with PIN1. PMID: 19439498

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Subcellular Location

Cytoplasm.

Protein Families

Sulfotransferase 1 family

Tissue Specificity

Highly expressed in the cerebral cortex and frontal lobe, slightly less in the cerebellum, occipital and temporal lobes, relatively low in the medulla and putamen, and lowest in the spinal cord. No expression detected in the pancreas. Highly expressed in

Database Links

HGNC: 14903

OMIM: 608359

KEGG: hsa:25830

STRING: 9606.ENSP00000332565

UniGene: Hs.189810

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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