SUSD4 Antibody

Code CSB-PA733164LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA733164LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SUSD4 Polyclonal antibody
Uniprot No.
Target Names
SUSD4
Alternative Names
SUSD4 antibody; UNQ196/PRO222 antibody; Sushi domain-containing protein 4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Sushi domain-containing protein 4 protein (56-290AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SUSD4 Antibody (Product code: CSB-PA733164LA01HU) is Non-conjugated. For SUSD4 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA733164LB01HU SUSD4 Antibody, HRP conjugated ELISA
FITC CSB-PA733164LC01HU SUSD4 Antibody, FITC conjugated
Biotin CSB-PA733164LD01HU SUSD4 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.
Gene References into Functions
  1. SUSD4 expression in both breast cancer cells and T cells infiltrating the tumor-associated stroma is useful to predict better prognosis of breast cancer patients. PMID: 26480818
  2. Membrane-bound isoform SUSD4a inhibits the classical and alternative complement pathways when expressed on the surface of Chinese hamster cells but not when expressed as a soluble, truncated protein. PMID: 23482636
  3. analysis of cloning, expression, refolding, and tissue distribution of Sushi domain-containing protein 4 PMID: 20348246
Subcellular Location
[Isoform 1]: Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.
Tissue Specificity
Isoform 3 is the predominant isoform in all tissues except cortex, cerebellum, kidney, and breast. Isoform 1 is found primarily in the esophagus and the brain.
Database Links

HGNC: 25470

OMIM: 615827

KEGG: hsa:55061

UniGene: Hs.497841

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