SV2B Antibody

Code CSB-PA022979LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Mouse brain tissue
    All lanes: SV2B antibody at 3.4µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 78, 61 kDa
    Observed band size: 78 kDa

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA022979LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SV2B Polyclonal antibody
Uniprot No.
Target Names
SV2B
Alternative Names
SV2B antibody; KIAA0735 antibody; Synaptic vesicle glycoprotein 2B antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Synaptic vesicle glycoprotein 2B protein (1-108AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SV2B Antibody (Product code: CSB-PA022979LA01HU) is Non-conjugated. For SV2B Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA022979LB01HU SV2B Antibody, HRP conjugated ELISA
FITC CSB-PA022979LC01HU SV2B Antibody, FITC conjugated
Biotin CSB-PA022979LD01HU SV2B Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Probably plays a role in the control of regulated secretion in neural and endocrine cells.; (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction. Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1.
Gene References into Functions
  1. In classical mesial temporal sclerosis 1A, the expression of SV2 isoforms is altered with a marked decrease of SV2B paralleling synaptic loss. PMID: 23617838
  2. Synaptic vesicle protein 2 binds adenine nucleotides PMID: 18524768
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein Families
Major facilitator superfamily
Database Links

HGNC: 16874

OMIM: 185861

KEGG: hsa:9899

STRING: 9606.ENSP00000332818

UniGene: Hs.21754

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