TAOK3 Antibody

Code CSB-PA003080
Size US$100
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  • Western Blot analysis of Jurkat cells using JIK Polyclonal Antibody
  • Western Blot analysis of Jurkat cells using JIK Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
TAOK3
Alternative Names
CTCL tumor antigen HD CL 09 antibody; CTCL-associated antigen HD-CL-09 antibody; Cutaneous T cell lymphoma tumor antigen HD CL 09 antibody; Cutaneous T-cell lymphoma-associated antigen HD-CL-09 antibody; Dendritic cell derived protein kinase antibody; Dendritic cell-derived protein kinase antibody; DKFZp666H245 antibody; DPK antibody; FLJ31808 antibody; hKFC A antibody; hKFC-A antibody; JIK antibody; JNK/SAPK inhibitory kinase antibody; JNK/SAPK-inhibitory kinase antibody; Jun kinase inhibitory kinase antibody; Jun kinase-inhibitory kinase antibody; KDS antibody; Kinase from chicken homolog A antibody; MAP3K18 antibody; Serine kinase antibody; Serine/threonine-protein kinase TAO3 antibody; STE20 like kinase antibody; TAO kinase 3 antibody; TAOK3 antibody; TAOK3_HUMAN antibody; Thousand and one amino acid protein 3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human JIK.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).
Gene References into Functions
  1. Results show that three CpG loci within FYN were hypermethylated in obese individuals, while obesity was associated with lower methylation of CpG loci within PIWIL4 and TAOK3. PMID: 26646899
Subcellular Location
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also localized to the peripheral cell membrane.
Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
Tissue Specificity
Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
Database Links

HGNC: 18133

OMIM: 616711

KEGG: hsa:51347

STRING: 9606.ENSP00000376317

UniGene: Hs.644420

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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