TDRKH Antibody

Datasheet

Code	CSB-PA023362GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q9Y2W6

Target Names

TDRKH

Alternative Names

2700091C21Rik antibody; Putative RNA binding protein antibody; RGD1311196 antibody; RP11-98D18.8 antibody; TDRD2 antibody; TDRD7 antibody; Tdrkh antibody; TDRKH_HUMAN antibody; Tudor and KH domain containing antibody; Tudor and KH domain-containing protein antibody; tudor domain containing 2 antibody; Tudor domain-containing protein 2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human TDRKH

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC,IF

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.

Gene References into Functions

Unlike most other Tudor domains TDRD2 preferentially recognizes an unmethylated arginine-rich sequence from PIWIL1. PMID: 29118143
Tudor domain proteins interact with arginine-glycine-rich motifs in a methylarginine-dependent manner. PMID: 15955813

Subcellular Location

Cytoplasm. Mitochondrion.

Protein Families

Tdrkh family

Database Links

HGNC: 11713

OMIM: 609501

KEGG: hsa:11022

STRING: 9606.ENSP00000357812

UniGene: Hs.144439

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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