TDRKH Antibody

Code CSB-PA023362GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TDRKH
Alternative Names
2700091C21Rik antibody; Putative RNA binding protein antibody; RGD1311196 antibody; RP11-98D18.8 antibody; TDRD2 antibody; TDRD7 antibody; Tdrkh antibody; TDRKH_HUMAN antibody; Tudor and KH domain containing antibody; Tudor and KH domain-containing protein antibody; tudor domain containing 2 antibody; Tudor domain-containing protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human TDRKH
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.
Gene References into Functions
  1. Unlike most other Tudor domains TDRD2 preferentially recognizes an unmethylated arginine-rich sequence from PIWIL1. PMID: 29118143
  2. Tudor domain proteins interact with arginine-glycine-rich motifs in a methylarginine-dependent manner. PMID: 15955813
Subcellular Location
Cytoplasm. Mitochondrion.
Protein Families
Tdrkh family
Database Links

HGNC: 11713

OMIM: 609501

KEGG: hsa:11022

STRING: 9606.ENSP00000357812

UniGene: Hs.144439

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