TECPR2 Antibody

Code CSB-PA023369LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA023369LA01HU at dilution of 1:100

  • Immunofluorescent analysis of PC-3 cells using CSB-PA023369LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TECPR2 Polyclonal antibody
Uniprot No.
Target Names
TECPR2
Alternative Names
TECPR2 antibody; KIAA0297 antibody; KIAA0329 antibody; Tectonin beta-propeller repeat-containing protein 2 antibody; WD repeat-containing protein KIAA0329/KIAA0297 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Tectonin beta-propeller repeat-containing protein 2 protein (516-783AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TECPR2 Antibody (Product code: CSB-PA023369LA01HU) is Non-conjugated. For TECPR2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA023369LB01HU TECPR2 Antibody, HRP conjugated ELISA
FITC CSB-PA023369LC01HU TECPR2 Antibody, FITC conjugated
Biotin CSB-PA023369LD01HU TECPR2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probably plays a role as positive regulator of autophagy.
Gene References into Functions
  1. Whole exome sequencing in an Italian pedigree suggests involvement of TECPR2 in a complex form of progressive motor neuron disease. PMID: 27406698
  2. The discovery of additional TECPR2 utations in non-Bukharian patients implies that this disease might be more common than previously appreciated PMID: 26542466
  3. Results show that TECPR2 associates with several trafficking components as SEC24D and cooperates with LC3C to regulate ER exit sites and ER export suggesting that TECPR2 functions as molecular scaffold linking early secretion pathway and autophagy. PMID: 26431026
  4. The discovered TECPR2 mutation implicates autophagy, a central intracellular mechanism, in spastic paraparesis. PMID: 23176824
Involvement in disease
Spastic paraplegia 49, autosomal recessive (SPG49)
Protein Families
WD repeat KIAA0329 family
Tissue Specificity
Detected in skin fibroblast (at protein level).
Database Links

HGNC: 19957

OMIM: 615000

KEGG: hsa:9895

STRING: 9606.ENSP00000352510

UniGene: Hs.195667

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