TEX11 Antibody

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Code CSB-PA023401GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TEX11
Alternative Names
TEX11 antibody; Testis-expressed protein 11 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Human TEX11
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles.
Form
Liquid
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers.
Gene References into Functions
  1. Through the translational regulation of novel RNA targets SMC1B and TEX11, DAZL may have a key role in regulating chromosome cohesion and DNA recombination; two processes fundamental in determining oocyte quality and whose establishment in foetal life may support lifelong fertility. PMID: 28364521
  2. Genetic screening of a large cohort of idiopathic infertile men reveals that TEX11 mutations, including frameshift and splicing acceptor site mutations, cause infertility in 1% of azoospermic men. PMID: 26136358
  3. TEX11 mutations, including frameshift and splicing acceptor site mutations, cause infertility in 1% of non-obstructive azoospermic men. PMID: 26136358
  4. hemizygous TEX11 mutations were a common cause of meiotic arrest and azoospermia in infertile men PMID: 25970010
  5. TEX11 was specifically expressed in human testis. PMID: 11279525

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Involvement in disease
Spermatogenic failure, X-linked, 2 (SPGFX2)
Subcellular Location
Chromosome.
Protein Families
SPO22 family
Tissue Specificity
Testis-specific. Not expressed in adult ovaries.
Database Links

HGNC: 11733

OMIM: 300311

KEGG: hsa:56159

STRING: 9606.ENSP00000340995

UniGene: Hs.121776

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