TIMM17A Antibody

Code CSB-PA023550GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TIMM17A
Alternative Names
Inner membrane preprotein translocase Tim17a antibody; Mitochondrial import inner membrane translocase subunit Tim17-A antibody; mitochondrial inner membrane translocase antibody; preprotein translocase antibody; TI17A_HUMAN antibody; TIM17 antibody; TIM17A antibody; TIMM17A antibody; translocase of inner mitochondrial membrane 17 homolog A (yeast) antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human TIMM17A
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Gene References into Functions
  1. TIMM17A has a profound impact on the cellular function of breast cancer cells. A decrease of TIMM17A expression is associated with the reduction of the aggressiveness of breast cancer cells. PMID: 26977020
  2. High TIMM17A expression is associated with adverse pathological outcomes in breast cancer. PMID: 20972741
  3. mRNA expression analysis and immunohistochemistry analysis in breast cancer tissues indicated that expression level of TIMM17A was directly correlated with tumor progression; survival analysis suggested TIMM17A was a prognosis factor in breast cancer. PMID: 20198662
  4. Tim17 is a conserved suppressor of mtDNA instability. PMID: 18826960
Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein Families
Tim17/Tim22/Tim23 family
Database Links

HGNC: 17315

OMIM: 605057

KEGG: hsa:10440

STRING: 9606.ENSP00000356256

UniGene: Hs.20716

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