TLE2 Antibody

Code CSB-PA050269
Size US$100
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Product Details

Uniprot No.
Target Names
TLE2
Alternative Names
enhancer of split groucho 2 antibody; enhancer of split groucho 2 antibody; Enhancer of split groucho-like protein 2 antibody; ESG antibody; ESG2 antibody; FLJ41188 antibody; GRG2 antibody; Groucho2 antibody; KIAA4188 antibody; MGC124808 antibody; mKIAA4188 antibody; Tle2 antibody; Tle2 protein antibody; TLE2_HUMAN antibody; transducin like enhancer of split 2 antibody; Transducin like enhancer of split 2, homolog of Drosophila E(sp1) antibody; Transducin like enhancer protein 2 antibody; Transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) antibody; Transducin-like enhancer of split 2, homolog of Drosophila E(spl) antibody; Transducin-like enhancer protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human TLE2.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Gene References into Functions
  1. Immunofluorescence analysis showed that TLE2 and RTA were colocalized in the same nuclear compartment in KSHV-infected cells. PMID: 19939918
Subcellular Location
Nucleus.
Protein Families
WD repeat Groucho/TLE family
Tissue Specificity
In all tissues examined, mostly in heart, brain, and muscle.
Database Links

HGNC: 11838

OMIM: 601041

KEGG: hsa:7089

STRING: 9606.ENSP00000262953

UniGene: Hs.332173

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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