TMEM98 Antibody

Code CSB-PA023901LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMEM98 Polyclonal antibody
Uniprot No.
Target Names
TMEM98
Alternative Names
TMEM98 antibody; UNQ536/PRO1079 antibody; Transmembrane protein 98 antibody; Protein TADA1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transmembrane protein 98 protein (25-226AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TMEM98 Antibody (Product code: CSB-PA023901LA01HU) is Non-conjugated. For TMEM98 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA023901LB01HU TMEM98 Antibody, HRP conjugated ELISA
FITC CSB-PA023901LC01HU TMEM98 Antibody, FITC conjugated
Biotin CSB-PA023901LD01HU TMEM98 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1).
Gene References into Functions
  1. siRNA-TMEM98 inhibited the invasion and migration of non-small cell lung cancer cells. PMID: 26884835
  2. Two novel TMEM98 mutations have been found in two pedigrees with autosomal dominant nanophthalmos. PMID: 26392740
  3. we identified a panel of novel common chemoresistance-associated genes and demonstrated that TMEM98 is a chemoresistance-conferring gene in hepatocellular carcinoma. PMID: 24608572
  4. A novel gene associated with nanophthalmos, TMEM98 most likely represents the cause of the disease. PMID: 24852644
Involvement in disease
Nanophthalmos 4 (NNO4)
Subcellular Location
Cell membrane; Single-pass type II membrane protein. Secreted. Secreted, extracellular exosome. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein Families
TMEM98 family
Tissue Specificity
Widely expressed with high expression in the ovary, pancreas and prostate. Expressed in the eye, particularly in corneal endothelium, iris, ciliary body, sclera, optic nerve, optic nerve head, and retina. Expressed by activated peripheral blood mononuclea
Database Links

HGNC: 24529

OMIM: 615949

KEGG: hsa:26022

STRING: 9606.ENSP00000378138

UniGene: Hs.3447

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