TMTC1 Antibody

Datasheet

Code	CSB-PA808537LA01HU
Size	US$166
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Image	Western blot All lanes: TMTC1 antibody at 6µg/ml + Mouse large intestine tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 99, 88, 74, 66, 26 kDa Observed band size: 99 kDa Immunofluorescent analysis of HepG2 cells using CSB-PA808537LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TMTC1 Polyclonal antibody

Uniprot No.

Q8IUR5

Target Names

TMTC1

Alternative Names

TMTC1 antibody; ARG99 antibody; Protein O-mannosyl-transferase TMTC1 antibody; EC 2.4.1.109 antibody; Transmembrane and TPR repeat-containing protein 1 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Transmembrane and TPR repeat-containing protein 1 protein (1-227AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TMTC1 Antibody (Product code: CSB-PA808537LA01HU) is Non-conjugated. For TMTC1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA808537LB01HU	TMTC1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA808537LC01HU	TMTC1 Antibody, FITC conjugated
Biotin	CSB-PA808537LD01HU	TMTC1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3.

Gene References into Functions

O-mannosylation pathway dedicated to cadherins/ protocadherins orchestrated by the four TMTC1-4 genes PMID: 28973932
findings provide an important link between aneuploidy and the stress pathways activated by Aurora B inhibition and also support the use of Aurora B inhibitors in combination therapy for treatment of cancer. PMID: 24764305

Subcellular Location

Membrane; Multi-pass membrane protein. Endoplasmic reticulum.

Protein Families

TMTC family

Database Links

HGNC: 24099

OMIM: 615855

KEGG: hsa:83857

STRING: 9606.ENSP00000442046

UniGene: Hs.401954

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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