TRAM2 Antibody

Datasheet

Code	CSB-PA624011LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA624011LA01HU at dilution of 1:100 Immunofluorescent analysis of MCF-7 cells using CSB-PA624011LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TRAM2 Polyclonal antibody

Uniprot No.

Q15035

Target Names

TRAM2

Alternative Names

TRAM2; KIAA0057; Translocating chain-associated membrane protein 2

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Translocating chain-associated membrane protein 2 protein (316-370AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TRAM2 Antibody (Product code: CSB-PA624011LA01HU) is Non-conjugated. For TRAM2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA624011LB01HU	TRAM2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA624011LC01HU	TRAM2 Antibody, FITC conjugated
Biotin	CSB-PA624011LD01HU	TRAM2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).

Gene References into Functions

TRAM2, as a part of the translocon, is required for the biosynthesis of type I collagen by coupling the activity of SERCA2b with the activity of the translocon PMID: 14749390

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

TRAM family

Database Links

HGNC: 16855

OMIM: 608485

KEGG: hsa:9697

STRING: 9606.ENSP00000182527

UniGene: Hs.520182

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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