TTLL7 Antibody

Code CSB-PA765082ESR1HU
Size US$166
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Image
  • Western blot
    All lanes: TTLL7 antibody at 2.6µg/ml + A549 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 103, 78, 93 kDa
    Observed band size: 103 kDa

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA765082ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA765082ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TTLL7 Polyclonal antibody
Uniprot No.
Target Names
TTLL7
Alternative Names
RP5-836J3.2 antibody; Testis development protein NYD-SP30 antibody; Ttll7 antibody; TTLL7_HUMAN antibody; Tubulin polyglutamylase TTLL7 antibody; Tubulin tyrosine ligase like family member 7 antibody; Tubulin--tyrosine ligase-like protein 7 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Tubulin polyglutamylase TTLL7 protein (1-260AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Mediates both ATP-dependent initiation and elongation steps of the polyglutamylation reaction. Preferentially modifies the beta-tubulin tail over an alpha-tail. Competes with monoglycylase TTLL3 for modification site on beta-tubulin substrate, thereby creating an anticorrelation between glycylation and glutamylation reactions. Required for neurite growth; responsible for the strong increase in tubulin polyglutamylation during postnatal neuronal maturation.
Subcellular Location
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, dendrite. Perikaryon.
Protein Families
Tubulin--tyrosine ligase family
Tissue Specificity
Highly expressed in the nervous system including spinal cord, thalamus, hippocampus, hypothalamus and cerebellum.
Database Links

HGNC: 26242

KEGG: hsa:79739

STRING: 9606.ENSP00000260505

UniGene: Hs.445826

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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