TTLL7 Antibody

Datasheet

Code	CSB-PA765082ESR2HU
Size	US$166
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Image	Western blot All lanes: TTLL7 antibody at 2.04µg/ml + Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 103, 78, 93 kDa Observed band size: 103 kDa Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA765082ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA765082ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TTLL7 Polyclonal antibody

Uniprot No.

Q6ZT98

Target Names

TTLL7

Alternative Names

RP5-836J3.2 antibody; Testis development protein NYD-SP30 antibody; Ttll7 antibody; TTLL7_HUMAN antibody; Tubulin polyglutamylase TTLL7 antibody; Tubulin tyrosine ligase like family member 7 antibody; Tubulin--tyrosine ligase-like protein 7 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Tubulin polyglutamylase TTLL7 protein (1-260AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Mediates both ATP-dependent initiation and elongation steps of the polyglutamylation reaction. Preferentially modifies the beta-tubulin tail over an alpha-tail. Competes with monoglycylase TTLL3 for modification site on beta-tubulin substrate, thereby creating an anticorrelation between glycylation and glutamylation reactions. Required for neurite growth; responsible for the strong increase in tubulin polyglutamylation during postnatal neuronal maturation.

Subcellular Location

Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, dendrite. Perikaryon.

Protein Families

Tubulin--tyrosine ligase family

Tissue Specificity

Highly expressed in the nervous system including spinal cord, thalamus, hippocampus, hypothalamus and cerebellum.

Database Links

HGNC: 26242

KEGG: hsa:79739

STRING: 9606.ENSP00000260505

UniGene: Hs.445826

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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