TXLNA Antibody

Code CSB-PA234430
Size US$166
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Image
  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A549 cells, 293T cells, Primary antibody: CSB-PA234430(TXLNA Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Product Details

Uniprot No.
Target Names
TXLNA
Alternative Names
Alpha-taxilin antibody; DKFZp451J0118 antibody; IL 14 antibody; IL14 antibody; interleukin 14 antibody; MGC11887 antibody; MGC118870 antibody; MGC118871 antibody; RP4-622L5.4 antibody; Taxilin alpha antibody; TXLN antibody; TXLNA antibody; TXLNA_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human TXLNA
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
Gene References into Functions
  1. intrathyroidal production of IL-14 and IL-16 associated with the pathogenesis of autoimmune thyroid disease PMID: 25940130
  2. Silencing of alpha-taxilin expression leads to increased release of infectious hepatitis C virus particles. PMID: 26527738
  3. alpha-taxilin interacts with SNX4 and plays a role in the recycling pathway of TfnR. PMID: 24690921
  4. alpha-taxilin plays an essential role for release of HBV-DNA containing particles. PMID: 23816704
  5. Alpha-taxilin is localized on intracellular components in a syntaxin-independent manner and that the alpha-taxilin-containing intracellular components are associated with the microtubule cytoskeleton. PMID: 22785156
  6. Increased alpha-taxilin protein expression is associated with the metastatic and invasive potential of renal cell cancer. PMID: 21551945
  7. alpha-taxilin may be involved in cell proliferation of hepatocellular carcinoma(HCC), and its expression can be a marker of malignant potential of HCC. PMID: 21042709
  8. identification of isoforms; interaction with syntaxin [alpha-taxilin] PMID: 15184072
  9. role for IL-14alpha (Txln gene product)in the development of both autoimmunity and lymphomagenesis PMID: 17015757
  10. increases in IL-14 transcript levels may play a role in alloantibody formation after renal transplantation PMID: 18645499
  11. IL-14a is important in the pathophysiology of Sjogren's disease PMID: 19038581
  12. analysis of a novel monoclonal antibody against interleukin-14alpha PMID: 19663695

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Protein Families
Taxilin family
Tissue Specificity
Ubiquitous, with much higher expression in heart, kidney, liver and pancreas.
Database Links

HGNC: 30685

OMIM: 608676

KEGG: hsa:200081

STRING: 9606.ENSP00000362711

UniGene: Hs.17987

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