TXNRD3 Antibody

Code CSB-PA025390GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TXNRD3
Alternative Names
TGR antibody; Thioredoxin and glutathione reductase antibody; Thioredoxin glutathione reductase antibody; Thioredoxin reductase 2 antibody; Thioredoxin reductase 3 antibody; Thioredoxin reductase TR2 antibody; TR2 antibody; TRXR3 antibody; TRXR3_HUMAN antibody; TXNRD3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human TXNRD3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components.
Gene References into Functions
  1. Findings represent the first characterization of hTGR and provide new insights into the reaction mechanism and the regulation of monothiol Grx-containing thioredoxin glutathione reductases. PMID: 29222842
  2. A role of GPx2, TrxR2 and TrxR3 in proliferation, apoptosis and, therefore, also during cancer development. PMID: 22683372
  3. This study pertains to use of non-AUG (CUG) start codon in mouse thioredoxin reductase 3 gene, and conservation of this site in other mammals. PMID: 20018845
Subcellular Location
Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum.
Protein Families
Class-I pyridine nucleotide-disulfide oxidoreductase family
Database Links

HGNC: 20667

OMIM: 606235

KEGG: hsa:114112

STRING: 9606.ENSP00000430031

UniGene: Hs.477475

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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