UNC45B Antibody

Code CSB-PA812884LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA812884LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) UNC45B Polyclonal antibody
Uniprot No.
Target Names
UNC45B
Alternative Names
Cardiomyopathy associated 4 antibody; CMYA4 antibody; FLJ38610 antibody; MGC119540 antibody; MGC119541 antibody; OTTHUMP00000163855 antibody; Protein unc 45 homolog B antibody; Protein unc-45 homolog B antibody; SMUNC45 antibody; Striated muscle UNC45 antibody; UN45B_HUMAN antibody; Unc 45 homolog B (C. elegans) antibody; Unc 45 homolog B antibody; UNC 45B antibody; UNC-45B antibody; UNC45 antibody; UNC45B antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein unc-45 homolog B protein (602-710AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The UNC45B Antibody (Product code: CSB-PA812884LA01HU) is Non-conjugated. For UNC45B Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA812884LB01HU UNC45B Antibody, HRP conjugated ELISA
FITC CSB-PA812884LC01HU UNC45B Antibody, FITC conjugated
Biotin CSB-PA812884LD01HU UNC45B Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
Gene References into Functions
  1. We have characterized a human UNC45B mutation in a Danish family with autosomal dominant cataract developing in early childhood. PMID: 24549050
  2. temperature-dependent structural changes in the UCS chaperone domain of UNC-45B that occur within a physiologically relevant heat-shock range. PMID: 25436418
Involvement in disease
Cataract 43 (CTRCT43)
Subcellular Location
Cytoplasm, cytosol.
Tissue Specificity
Expressed in eye lens tissues.
Database Links

HGNC: 14304

OMIM: 611220

KEGG: hsa:146862

STRING: 9606.ENSP00000268876

UniGene: Hs.379636

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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