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UNC45B Antibody, FITC conjugated

Datasheet
Code CSB-PA812884LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) UNC45B Polyclonal antibody
Uniprot No.
Q8IWX7
Target Names
UNC45B
Alternative Names
Cardiomyopathy associated 4 antibody; CMYA4 antibody; FLJ38610 antibody; MGC119540 antibody; MGC119541 antibody; OTTHUMP00000163855 antibody; Protein unc 45 homolog B antibody; Protein unc-45 homolog B antibody; SMUNC45 antibody; Striated muscle UNC45 antibody; UN45B_HUMAN antibody; Unc 45 homolog B (C. elegans) antibody; Unc 45 homolog B antibody; UNC 45B antibody; UNC-45B antibody; UNC45 antibody; UNC45B antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein unc-45 homolog B protein (602-710AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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UNC45B Antibodies

UNC45B Proteins

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Target Background

Function
Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
Gene References into Functions
  1. We have characterized a human UNC45B mutation in a Danish family with autosomal dominant cataract developing in early childhood. PMID: 24549050
  2. temperature-dependent structural changes in the UCS chaperone domain of UNC-45B that occur within a physiologically relevant heat-shock range. PMID: 25436418
Involvement in disease
Cataract 43 (CTRCT43)
Subcellular Location
Cytoplasm, cytosol.
Tissue Specificity
Expressed in eye lens tissues.
Database Links

HGNC: 14304

OMIM: 611220

KEGG: hsa:146862

STRING: 9606.ENSP00000268876

UniGene: Hs.379636

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