USP34 Antibody

Code CSB-PA025725GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
USP34
Alternative Names
Deubiquitinating enzyme 34 antibody; FLJ43910 antibody; KIAA0570 antibody; KIAA0729 antibody; MGC104459 antibody; Ubiquitin carboxyl terminal hydrolase 34 antibody; Ubiquitin carboxyl-terminal hydrolase 34 antibody; Ubiquitin specific processing protease 34 antibody; Ubiquitin specific protease 34 antibody; Ubiquitin thioesterase 34 antibody; Ubiquitin thiolesterase 34 antibody; Ubiquitin-specific-processing protease 34 antibody; UBP34_HUMAN antibody; USP 34 antibody; Usp34 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Human USP34
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Gene References into Functions
  1. the role of USP34 on epithelial-mesenchymal (EMT) induction and its effects on mammary epithelial stem cells, was investigated. PMID: 28499884
  2. CONCLUSIONS: USP34 gene polymorphisms (rs17008097 and rs17008940) may not be associated with Polycystic ovary syndrome in the Han Chinese women. PMID: 25975428
Protein Families
Peptidase C19 family
Tissue Specificity
Expressed in brain at low level.
Database Links

HGNC: 20066

OMIM: 615295

KEGG: hsa:9736

STRING: 9606.ENSP00000381577

UniGene: Hs.644708

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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