USP42 Antibody

Code CSB-PA151486
Size US$297
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  • Western blot analysis of extracts from HT-29 cells, using USP42 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) USP42 Polyclonal antibody
Uniprot No.
Target Names
USP42
Alternative Names
Deubiquitinating enzyme 42 antibody; FLJ12697 antibody; Ubiquitin carboxyl-terminal hydrolase 42 antibody; ubiquitin specific peptidase 42 antibody; Ubiquitin thiolesterase 42 antibody; Ubiquitin-specific-processing protease 42 antibody; UBP42 antibody; UBP42_HUMAN antibody; USP42 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human USP42.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Deubiquitinating enzyme which may play an important role during spermatogenesis.
Gene References into Functions
  1. USP42 overexpression could be a potential prognostic marker for GC, regulate the survival and invasive properties of GC, and may represent a novel therapeutic molecular target for this tumor. PMID: 27030989
  2. a role for USP42 in regulating transcription by deubiquitylating histones PMID: 25336640
  3. we report, for the first time, the identification of a RUNX1-USP42 fusion transcript detected at diagnosis in a child with AML and del(5). PMID: 24673627
  4. the function of USP42 is required to allow the rapid activation of p53-dependent transcription and a p53-dependent cell-cycle arrest in response to stress. PMID: 22085928
Protein Families
Peptidase C19 family
Tissue Specificity
Broadly expressed.
Database Links

HGNC: 20068

KEGG: hsa:84132

STRING: 9606.ENSP00000301962

UniGene: Hs.31856

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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