USP44 Antibody

1. These data imply a complex picture where regulating factors such as OCT4 may interact with other epigenetic mechanisms to regulate USP44 expression in pluripotent stem cells and testes. PMID: 28520534
2. USP44 protein was widely expressed in most of the tumor samples and no clear association could be established between its expression and DNA ploidy status or tumor size PMID: 28492742
3. In summary, we report that the combination of USP44 expression and DNA ploidy status might serve as an independent prognostic marker in gastric cancer. PMID: 28544703
4. USP44 contributes to N-CoR functions in regulating gene expression and is required for efficient invasiveness of triple-negative breast cancer cells. PMID: 27880911
5. USP44+ Cancer Stem Cell Subclones Contribute to Breast Cancer Aggressiveness by Promoting Vasculogenic Mimicry PMID: 26232424
6. USP44 is epigenetically inactivated in colorectal adenomas, but this alone is not sufficient to cause aneuploidy in colorectal neoplasia. PMID: 24837038
7. findings implicate USP44 in negative regulation of the RNF8/RNF168 pathway PMID: 23615962
8. Data identify Cdc20, USP44, and Wee1 as relevant Fcp1 targets. PMID: 22692537
9. These data are consistent with an important role for USP44 in regulating Cdc20-APC/C activity and suggest that high levels of this enzyme may contribute to the pathogenesis of T-cell leukemias. PMID: 21853124
10. a dynamic balance of ubiquitination by the APC and deubiquitination by USP44 contributes to the generation of the switch-like transition controlling anaphase entry PMID: 17443180

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HGNC: 20064

OMIM: 610993

KEGG: hsa:84101

STRING: 9606.ENSP00000258499

UniGene: Hs.646421