VEZT Antibody

Code CSB-PA025846GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
VEZT
Alternative Names
VEZT; Vezatin
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human VEZT
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. Required for morphogenesis of the preimplantation embryo, and for the implantation process.; (Microbial infection) In case of Listeria infection, promotes bacterial internalization by participating in myosin VIIa recruitment to the entry site.
Gene References into Functions
  1. This study identified the most effective small activating RNA via real-time PCR and Western blot. The selected small activating RNA inhibited the growth, invasion and migration of gastric cancer cells by specially reactivating VEZT. PMID: 27856244
  2. VEZT expression levels can be considered as a biomarker for gastric cancer progression, lymphatic metastasis and as a novel independent prognostic factor. PMID: 25792470
  3. vezatin and nearby SNP rs10859871 may have a role in endometriosis [meta-analysis] PMID: 25678572
  4. VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer. PMID: 24069310
  5. function of mouse vezatin in mouse blastocyst morphogenesis PMID: 16199027
  6. miR-43c directly targets adherens junctions' transmembrane protein (VEZT) and suppresses VEZT protein expression. PMID: 21156161

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Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell projection, stereocilium membrane. Cell junction, adherens junction. Nucleus. Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein Families
Vezatin family
Database Links

HGNC: 18258

KEGG: hsa:55591

STRING: 9606.ENSP00000410083

UniGene: Hs.24135

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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