VPS72 Antibody

Code CSB-PA050222
Size US$100
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  • Western blot analysis of 293T lysis using VPS72 antibody.

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Product Details

Uniprot No.
Target Names
VPS72
Alternative Names
CFL1 antibody; HGNC11644 antibody; Protein YL-1 antibody; Swc2 antibody; TCFL1 antibody; Transcription factor like 1 (YL1) antibody; Transcription Factor Like 1 antibody; Transcription factor-like 1 antibody; Vacuolar protein sorting 72 (yeast) antibody; Vacuolar protein sorting 72 homolog (S. cerevisiae) antibody; Vacuolar protein sorting associated protein 72 homolog antibody; Vacuolar protein sorting-associated protein 72 homolog antibody; VPS72 antibody; VPS72_HUMAN antibody; YL-1 antibody; YL1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the Internal region of Human VPS72.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.
Gene References into Functions
  1. The 2.7-A-resolution crystal structure of the human YL1-H2A.Z-H2B complex shows that YL1 binding, similarly to ANP32E binding, triggers an extension of the H2A.Z alphaC helix. PMID: 26974126
  2. Results identify YL1 as a subunit of the TRRAP/TIP60 HAT complex, and also as a component of a novel mammalian multiprotein complex that includes the SNF2-related helicase SRCAP. PMID: 15647280
Subcellular Location
Nucleus.
Protein Families
VPS72/YL1 family
Database Links

HGNC: 11644

OMIM: 600607

KEGG: hsa:6944

STRING: 9606.ENSP00000357887

UniGene: Hs.2430

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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