VPS72 Antibody

Code CSB-PA025919GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
VPS72
Alternative Names
CFL1 antibody; HGNC11644 antibody; Protein YL-1 antibody; Swc2 antibody; TCFL1 antibody; Transcription factor like 1 (YL1) antibody; Transcription Factor Like 1 antibody; Transcription factor-like 1 antibody; Vacuolar protein sorting 72 (yeast) antibody; Vacuolar protein sorting 72 homolog (S. cerevisiae) antibody; Vacuolar protein sorting associated protein 72 homolog antibody; Vacuolar protein sorting-associated protein 72 homolog antibody; VPS72 antibody; VPS72_HUMAN antibody; YL-1 antibody; YL1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human VPS72
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.
Gene References into Functions
  1. The 2.7-A-resolution crystal structure of the human YL1-H2A.Z-H2B complex shows that YL1 binding, similarly to ANP32E binding, triggers an extension of the H2A.Z alphaC helix. PMID: 26974126
  2. Results identify YL1 as a subunit of the TRRAP/TIP60 HAT complex, and also as a component of a novel mammalian multiprotein complex that includes the SNF2-related helicase SRCAP. PMID: 15647280
Subcellular Location
Nucleus.
Protein Families
VPS72/YL1 family
Database Links

HGNC: 11644

OMIM: 600607

KEGG: hsa:6944

STRING: 9606.ENSP00000357887

UniGene: Hs.2430

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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