WBSCR17 Antibody

Code CSB-PA025982GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
GALNT17
Alternative Names
GALNT17 antibody; WBSCR17Polypeptide N-acetylgalactosaminyltransferase 17 antibody; EC 2.4.1.41 antibody; Polypeptide GalNAc transferase-like protein 3 antibody; GalNAc-T-like protein 3 antibody; pp-GaNTase-like protein 3 antibody; Protein-UDP acetylgalactosaminyltransferase-like protein 3 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3 antibody; Williams-Beuren syndrome chromosomal region 17 protein antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human WBSCR17
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
Gene References into Functions
  1. GWA study identified maternal genetic effects not previously identified in ASD at a locus in WBSCR17. PMID: 27876814
  2. a subset of O-glycosylation produced by WBSCR17 controls dynamic membrane trafficking, probably between the cell surface and the late endosomes through macropinocytosis PMID: 22787146
Involvement in disease
WBSCR17 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein Families
Glycosyltransferase 2 family, GalNAc-T subfamily
Tissue Specificity
Highly expressed in brain and heart. Weakly expressed in kidney, liver, lung and spleen.
Database Links

HGNC: 16347

OMIM: 615137

KEGG: hsa:64409

STRING: 9606.ENSP00000329654

UniGene: Hs.488591

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