ZBTB46 Antibody

Code CSB-PA803124HA01HU
Size US$166
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  • Western blot
    All lanes: ZBTB46 antibody at 2μg/ml
    Lane 1: Mouse heart tissue
    Lane 2: Mouse liver tissue
    Lane 3: Mouse kidney tissue
    Lane 4: 293T whole cell lysate
    Lane 5: SH-SY5Y whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 65 kDa
    Observed band size: 65 kDa

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA803124HA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA803124HA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZBTB46 Polyclonal antibody
Uniprot No.
Target Names
ZBTB46
Alternative Names
ZBTB46 antibody; BTBD4 antibody; ZNF340 antibody; Zinc finger and BTB domain-containing protein 46 antibody; BTB-ZF protein expressed in effector lymphocytes antibody; BZEL antibody; BTB/POZ domain-containing protein 4 antibody; Zinc finger protein 340 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Zinc finger and BTB domain-containing protein 46 protein (174-362AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ZBTB46 Antibody (Product code: CSB-PA803124HA01HU) is Non-conjugated. For ZBTB46 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA803124HB01HU ZBTB46 Antibody, HRP conjugated ELISA
FITC CSB-PA803124HC01HU ZBTB46 Antibody, FITC conjugated
Biotin CSB-PA803124HD01HU ZBTB46 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The ZBTB46 antibody is raised in the rabbit against a partial protein corresponding to 174-362 amnio acids of the human ZBTB46 protein. It is available as the unconjugated IgG isoform. Its purity is 95%+ using protein G purified. This antibody is reactive to human and mouse ZBTB46 protein. And it has been quality control tested in ELISA, WB, and IHC applications. Its target protein ZBTB46 is highly expressed in quiescent endothelial cells and functions as a shear-sensitive transcription factor suppressing endothelial cell proliferation through the expression regulation of cell cycle proteins.

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Target Background

Function
Functions as a transcriptional repressor for PRDM1.
Gene References into Functions
  1. Authors report a novel tumor promoter, ZBTB46, which is negatively regulated by AR signaling via microRNA (miR)-1-mediated downregulation. ZBTB46 is associated with malignant prostate cancer and is essential for metastasis. PMID: 28692046
  2. A single nucleotide polymorphisn in ZBTB46, rs6062314, is associated with an increased genetic risk for multiple sclerosis. PMID: 23739915
Subcellular Location
Nucleus.
Database Links

HGNC: 16094

OMIM: 614639

KEGG: hsa:140685

STRING: 9606.ENSP00000245663

UniGene: Hs.585028

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