ZHX1 Antibody

1. ZHX1 expression is correlated with renal cell carcinoma progression and poor survival. PMID: 28152006
2. ZHX1 was found to play essential roles in the proliferation, migration, and invasion of cholangiocarcinoma cells, and its effect on the proliferation was mediated partially through EGR1. PMID: 27835650
3. together, this study demonstrates that ZHX1 plays crucial roles in the progression of glioblastoma, and its findings suggest that ZHX1 be viewed as a potential prognostic maker and therapeutic target of glioblastoma. PMID: 28351300
4. miR-199a-3p may function as a novel tumor promoter in gastric cancer and its oncogenic activity may involve the direct targeting and inhibition of ZHX1 PMID: 25448600
5. Low expression of ZHX1 may be responsible for hepatocarcinogenesis. PMID: 24064680
6. Study showed that ZHX1 is SUMOylated by Ubc9 with SUMO1 at the sites K159, K454, and K626 and that the SUMOylation of ZHX1 regulated the stability, ubiquitination and transcriptional activity of ZHX1. PMID: 23686912
7. This study characterized features of ZHX-1 involved in nuclear localization, dimerization, and transcriptional activity, and mapped these domains. PMID: 12237128
8. a search of ZHX1-interacting proteins using a yeast two-hybrid system PMID: 12659632
9. ZHX proteins 1, 2 and 3 are major transcriptional mediators of podocyte disease PMID: 17056598
10. ZHX1 enhanced the transcriptional repression mediated by DNMT3B when DNMT3B is directly targeted to DNA. These results showed for the first the direct linkage between DNMT and zinc-fingers homeoboxes protein, leading to enhanced gene silencing by DNMT3B PMID: 17303076
11. structure of the tandem zinc-finger region of human ZHX1 PMID: 19348505

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HGNC: 12871

OMIM: 604764

KEGG: hsa:11244

STRING: 9606.ENSP00000297857

UniGene: Hs.521800