ZNF24 Antibody

Datasheet

Code	CSB-PA026606ESR2HU
Size	US$166
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Image	Western blot All lanes: ZNF24 antibody at 2.88µg/ml Lane 1: 293T whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 43, 23 kDa Observed band size: 43 kDa Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA026606ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA026606ESR2HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ZNF24 Polyclonal antibody

Uniprot No.

P17028

Target Names

ZNF24

Alternative Names

KOX17 antibody; Retinoic acid suppression protein A antibody; RSG A antibody; RSG-A antibody; RSGA antibody; Zfp191 antibody; Zinc finger and SCAN domain containing protein 3 antibody; Zinc finger and SCAN domain-containing protein 3 antibody; Zinc finger protein 191 antibody; Zinc finger protein 24 antibody; Zinc finger protein KOX17 antibody; ZNF 24 antibody; ZNF191 antibody; ZNF24 antibody; ZNF24_HUMAN antibody; ZSCAN 3 antibody; ZSCAN3 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Zinc finger protein 24 protein (169-368AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro.

Gene References into Functions

miR-940 promoted gastric cancer progression by directly downregulating ZNF24 expression. PMID: 26317898
In vivo, knockdown of ZNF24 specifically in microvascular endothelial cells led to significantly decreased formation of functional vascular networks. PMID: 25550468
results suggest that consecutive ZF1-2 is critical for the regulation of ZNF24 nuclear localization and its transactivation function. PMID: 24224020
ZNF24 may be implicated in transcriptional regulation of genes associated with oncogenesis via interaction with H2A.Z. PMID: 22678762
ZNF191 can directly bind to the CTNNB1 promoter and activate the expression of beta-catenin and its downstream target genes such as cyclin D1 in hepatoma cell lines. PMID: 22213192
These data suggest that ZNF24 is involved in negative regulation of PDGFR-beta and may represent a novel repressor of PDGFR-beta transcription. PMID: 20510677
Overexpression and purification of single zinc finger peptides of ZNF191 were performed. PMID: 17270462
ZNF191 is a pleiotropic factor that has a role in hematopoiesis, brain development, and tumor growth. PMID: 19463170
Data confirm ZNF191 as an essential factor acting for the promotion of the cell cycle and thus maintenance in the progenitor stage. PMID: 19544452

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Subcellular Location

Nucleus.

Protein Families

Krueppel C2H2-type zinc-finger protein family

Tissue Specificity

Expressed in many tissues except in heart.

Database Links

HGNC: 13032

OMIM: 194534

KEGG: hsa:7572

STRING: 9606.ENSP00000261332

UniGene: Hs.514802

Promotions

Transmembrane Protein Questionnaire with Gifts

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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