Recombinant Mouse C-C motif chemokine 27 protein(Ccl27) (Active)

In Stock
Code CSB-AP001381MO
Product Type Chemokine
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q9Z1X0
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias CC chemokine ILC, CTACK, ESkine, IL-11 R-alpha-locus chemokine, ALP
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 10-100 ng/ml.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence LPLPSSTSCC TQLYRQPLPS RLLRRIVHME LQEADGDCHL QAVVLHLARR SVCVHPQNRS LARWLERQGK RLQGTVPSLN LVLQKKMYSN PQQQN
Research Area Immunology
Source E.coli
Gene Names Ccl27
Expression Region 26-120aa
Tag Info Tag-Free
Mol. Weight 10.9 kDa
Protein Description Partial of NM_011336
PubMed ID 10329455; 10556532; 10588729; 16141072; 15489334; 10559234; 12133963
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Function Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10.
Subcellular Location Isoform 1: Secreted, Nucleus
Protein Families Intercrine beta (chemokine CC) family
Tissue Specificity Isoform 1 is predominantly expressed in placenta and weakly in skin. Isoform 2 is predominantly expressed in testes and brain, weakly in kidney and liver and even lower in heart and muscle. Low expression of both isoforms in other tissues.
Database Links

KEGG: mmu:100039863

STRING: 10090.ENSMUSP00000137284

UniGene: Mm.335946

Pathway Chemokine signaling pathway

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