Mst77F Antibody

Code CSB-PA323476XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Mst77F Polyclonal antibody
Uniprot No.
Target Names
Mst77F
Alternative Names
Mst77F antibody; 18c antibody; anon-77F antibody; CG3354Histone-like protein 18C antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Mst77F protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Not known. Encoded in the intron of cAMP-dependent protein kinase regulatory chain type I.
Gene References into Functions
  1. Data demonstrate that Mst77F is required for the proper compaction of spermatid chromatin following the histone-to-protamine transition, and show that Mst77F is proteolytically processed during spermiogenesis, in a way remarkably similar to mammalian P2. PMID: 27810970
  2. An intrinsically unstructured domain in the C-terminus of Mst77F binds DNA via electrostatic interaction. This binding results in structural reorganization of the domain, which induces interaction with an N-terminal region of the protein. PMID: 25735749
  3. Spermatids of ms(3)nc3 (Mst77F(1)) mutants show disturbed nuclear shaping, instability of perinuclear microtubules but no obvious chromatin condensation defects. PMID: 20138392
  4. identification of functional Mst77Y genes PMID: 19897751
Database Links

KEGG: dme:Dmel_CG3354

STRING: 7227.FBpp0077928

UniGene: Dm.2510

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