tws Antibody

Datasheet

Code	CSB-PA330653XA01DLU
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) tws Polyclonal antibody

Uniprot No.

P36872

Target Names

tws

Alternative Names

tws antibody; aar antibody; Pp2A-85F antibody; CG6235Protein phosphatase PP2A 55 kDa regulatory subunit antibody; PR55 antibody; Protein phosphatase PP2A regulatory subunit B antibody; Protein twins antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) tws protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Could perform a substrate recognition function or could be responsible for targeting the enzyme complex to the appropriate subcellular compartment.

Gene References into Functions

Mutations in tws cause high frequencies of chromosome aberrations. Tws is required for activation of the G2/M DNA damage checkpoint. PMID: 28040742
The PP2A complex plays a novel role in differentiating tissues to promote developmentally controlled quiescence through the regulation of Cyclin E/Cdk2 activity. PMID: 26253406
Drosophila protein PP2A is a liprin-alpha-interacting protein that mediates interaction between the two proteins. PMID: 24948803
E4orf4 has a role in inducing PP2A- and Src-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster PMID: 23613593
Greatwall and Endos act to promote the inactivation of PP2A-Twins/B55 in Drosophila PMID: 21852956
PP2A-B' knockout flies have elevated S6K phosphorylation and exhibit phenotypes typical of elevated insulin signaling such as reduced total body triglycerides and reduced longevity. PMID: 20444422
Data demonstrate that PP2A is required for Wnt/beta-catenin signaling in Drosophila. PMID: 19556239

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Protein Families

Phosphatase 2A regulatory subunit B family

Database Links

KEGG: dme:Dmel_CG6235

STRING: 7227.FBpp0081665

UniGene: Dm.3826

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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tws Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background